{"id":8874,"date":"2024-07-31T18:49:29","date_gmt":"2024-07-31T18:49:29","guid":{"rendered":"https:\/\/michaelturnermd.com\/lateststagging\/?post_type=product&#038;p=8874"},"modified":"2024-07-31T18:49:36","modified_gmt":"2024-07-31T18:49:36","slug":"vitamin-d-k-4000-i-u","status":"publish","type":"product","link":"https:\/\/michaelturnermd.com\/lateststagging\/product\/vitamin-d-k-4000-i-u\/","title":{"rendered":"Vitamin D + K 4,000 I.U."},"content":{"rendered":"<p>You\u2019ve probably heard about Vitamin D by now, especially how important it is for your immune system, but did you know the \u201csunshine vitamin\u201d is also helpful for many other things? Vitamin D plays an important role in thyroid hormone production, and sluggish thyroid is very common, as are suboptimal Vitamin D levels. If you live above the 37th parallel, are cooped up indoors most of the year, or have a darker skin tone, there\u2019s a good chance you might need more of this.<\/p>\n<p>The optimal range is between 50-80 ng\/ml, and if you struggle with\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23999998\/\" target=\"_blank\" rel=\"noopener\">autoimmunity,<\/a>\u00a0you\u2019ll want yours at the higher end of the range. Vitamin D can also help elevate\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9539254\/\" target=\"_blank\" rel=\"noopener\">your mood<\/a>\u00a0(hello winter blues) and can help\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20302551\/\" target=\"_blank\" rel=\"noopener\">strengthen your bones<\/a>, but you&#8217;ll want to pair it with K2 to help keep calcium in the right place.<\/p>\n<div class=\"sub-content benifits\">\n<ul>\n<li>Promote healthy calcium utilization to maintain bone health<sup>\u2021<\/sup><\/li>\n<li>Supports vascular tissue to support healthy arterial calcium balance and vascular elasticity<sup>\u2021<\/sup><\/li>\n<li>Supports immune function with vitamin D<sub>3<\/sub><sup>\u2021<\/sup><\/li>\n<\/ul>\n<\/div>\n<div class=\"sub-content features\">\n<ul>\n<li>Provides vitamin D<sub>3<\/sub>\u00a0and vitamin K<sub>2<\/sub>\u00a0in one convenient capsule<\/li>\n<li>100 mcg of biologically active all-trans vitamin K<sub>2<\/sub>\u00a0(MK-7) per capsule<\/li>\n<li>Made with hypoallergenic ingredients<\/li>\n<\/ul>\n<h2>Verifiable Science<\/h2>\n<p>Vitamin K<sub>2<\/sub>\u00a0(menaquinone-7) is a fat-soluble nutrient with an important role in maintaining arterial calcium balance and vascular elasticity.<sup>1-12<\/sup>\u00a0In a systematic review involving five studies, higher intakes of vitamin K<sub>2<\/sub>\u00a0were associated with cardiovascular health.<sup>10<\/sup>\u00a0In an observational study involving 564 postmenopausal women, higher intake of vitamin K<sub>2<\/sub>\u00a0was associated with calcium balance in the vascular tissue.<sup>8<\/sup>\u00a0One of the primary functions of vitamin K<sub>2<\/sub>\u00a0is to support the carboxylation of matrix Gla-protein (MGP), a key protein involved in calcium balance.<sup>11<\/sup>\u00a0Accordingly, several studies indicate that Vitamin K<sub>2<\/sub>\u00a0also supports proper utilization of calcium in bone. Clinical research indicates that obtaining adequate amounts helps to maintain bone health.<sup>1-6<\/sup>\u00a0Vitamin K<sub>2<\/sub>\u00a0and vitamin D<sub>3<\/sub>\u00a0both participate in the regulation of osteocalcin, a biomarker of bone formation.<sup>1,13\u2021<\/sup><\/p>\n<h2>References<\/h2>\n<ol>\n<li>Gropper SAS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th Ed. Chapter 10, pp. 412-414. Wadsworth\/Cengage Learning, Australia. c.2009.<\/li>\n<li>El Borolossy R, El-Farsy MS. Eur J Clin Nutr. 2022 Jun;76(6):848-854.<\/li>\n<li>Qiu C, Zheng H, Tao H, et al. Mol Cell Biochem. 2017 Sep;433(1-2):149-159.<\/li>\n<li>Yamaguchi M, Sugimoto E, Hachiya S. Mol Cell Biochem. 2001 Jul;223(1-2):131-7.<\/li>\n<li>Zhang Y, Liu Z, Duan L, et al. Calcif Tissue Int. 2020 May;106(5):476-485.<\/li>\n<li>Knapen MH, Drummen NE, Smit E, et al. Osteoporos Int. 2013 Sep;24(9):2499-507.<\/li>\n<li>Knapen MH, Braam LA, Drummen NE, et al. Thromb Haemost. 2015 May;113(5):1135-44.<\/li>\n<li>Beulens JW, Bots ML, Atsma F, et al. Atherosclerosis. 2009 Apr;203(2):489-93.<\/li>\n<li>Mansour AG, Hariri E, Daaboul Y, et al. J Am Soc Hypertens. 2017 Sep;11(9):589-597.<\/li>\n<li>Rees K, Guraewal S, Wong YL, et al. Maturitas. 2010 Oct;67(2):121-8.<\/li>\n<li>Dalmeijer GW, van der Schouw YT, Magdeleyns E. Atherosclerosis. 2012 Dec;225(2):397-402.<\/li>\n<li>Vermeer C and Vik H. Vascul Dis Ther. 2020;5: doi: 10.15761\/VDT.1000179.<\/li>\n<li>Gigante A, Brug\u00c3\u00a8 F, Cecconi S, et al. J Tissue Eng Regen Med. 2015 Jun;9(6):691-701.<\/li>\n<\/ol>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>You\u2019ve probably heard about Vitamin D by now, especially how important it is for your immune system, but did you know the \u201csunshine vitamin\u201d is also helpful for many other things? Vitamin D plays an important role in thyroid hormone production, and sluggish thyroid is very common, as are suboptimal Vitamin D levels. If you [&hellip;]<\/p>\n","protected":false},"featured_media":8893,"comment_status":"open","ping_status":"closed","template":"","meta":{"pmpro_default_level":""},"product_brand":[],"product_cat":[49],"product_tag":[85],"class_list":{"0":"post-8874","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","7":"product_tag-womens-health","8":"pmpro-has-access","10":"first","11":"instock","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product\/8874","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/comments?post=8874"}],"version-history":[{"count":0,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product\/8874\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/media\/8893"}],"wp:attachment":[{"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/media?parent=8874"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product_brand?post=8874"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product_cat?post=8874"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/michaelturnermd.com\/lateststagging\/wp-json\/wp\/v2\/product_tag?post=8874"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}